ბახტრიონის ქ. N26, ბ. 85., თბილისი, საქართველო (+995)

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1 n ERSONAL INFORMATION ლუიზა გაბუნია ბახტრიონის ქ. N26, ბ. 85., თბილისი, საქართველო (+995) დაბადების დრო: 07/10/1966 დაბადების ადგილი: სოხუმი, საქართველო ქვეყნა და ეროვნება: საქართველო, ქართველი. ოჯახური მდგომარეობა: დაოჯახებული, ორი შვილი განათლება: თბილსის სახელმწიფო სამედიცინო უნივერსიტეტის მედიცინის ფაკულტეტი. სამუშაო გამოცდილება ქ. მოსკოვის სამეცნიერო კვლევით ინსტიტუტში სწავლობდა ასპირანტურაში და მოიპოვა მედიცინის აკადემიური დოქტორის წოდება (PdD) მედიცინაში თემაზე Pharmacology of the new combined agent Metacizin ; ( PhD in Medicine N ; the priority patent Russian Federation N Combined anti-arrhythmic drug metacizin - ( )) ქ. მოსკოვის სამეცნიერო კვლევით ინსტიტუტში მუშაობდა უფროს მეცნიერ თანამშრომლად; თსსუ ის სამედიცინო ფარმაკოლოგიის ასისტენტ პროფესორი; 1999 დღემდე საქართველოს ფარმაკოლოგთა საზოგადოების წევრი, რომელიც თავის მხრივ კლინიკური ფარმაკოლოგიისა და ფარმაკოთერაპიის ევროპული ასოციაციის წევრია (EACPT) და ასევე, სამედიცინო მეცნიერებათა საერთაშორისო ორგანიზაციის საზოგადოების (CIOMS) წევრი კომპანია MPHARMA ის სამედიცინო კონსულტატი და ტრენინგის ხელმძღვანელი; დღედე თსსუ ის სამედიცინო ფარმაკოლოგიის დეპარტამენტის ასოცირებული პროფესორი; 2012 დღემდე სამეცნიერო უნარ ჩვევბის ცენტრის დორექტორი;

2 2016 დღემდე ბიოსამედიცინო კვლევების განვითარების ასოციაციის დამფუძნებელი და პრეზიდენტი 2015 დღემდე თსსუ ის ამერიკული პროგრამის მოწვეული ლექტორი. დღესდღეობით არსებული პოზიციები: თსსუ ის სამედიცინო ფარმაკოლოგიის დეპარტამენტის ასოცირებული პროფესორი, სამეცნიერო უნარ ჩვევბის ცენტრის დირექტორი. სამეცნიერი შრომების სია 1.L.Gabunia et al. Influence of Carvedilole and Nebivolole on Blood Biochemical Indices of Experimental Rabbits under Electrical Stress. //Bulletin of The Georgian Academy of Sciences, 2005, 172, N3, 2. L.Gabunia et al. Influence of Nebivolole and Carvedilole on Rheological Properties of Experimental Rabbits Blood, Aggregation-Adhesion of Thrombocytes and Osmotic Resistance-Hemolysis Degree of Erythrocytes against a Background of Electrical Stress. //BULLETIN OF THE GEORGIAN ACADEMY OF SCIENCES, 2006, 173, N1, 3. L.Gabunia et al. Influence of Pernilla Oil on Lipid Metabolism and Rheological Properties of Blood. // J. Allergology andimmunology. 2006, v. 7, #5. 4. L.Gabunia et al. Comparative Influence of Karvedilol and Aspirin on Platelet Quantitative qualitative Indices and Blood IonExchange under The Conditions of Experimental Electrical Stress. // J. Allergology and Immunology. 2006, v. 7, #5. 5. L.Gabunia et al. Influence of Dilatrend on Rheological Properties of Blood under The Conditions of Experimental Electrical Stress //Bulletin of the Georgian Academy of Sciences. Series of Biology, 2006, #4. (V. 32), pp L.Gabunia et al. Effect of Carvedilol and Nebivolol combination on experimental rabbits blood rheology and platelets aggregation adhesion on background of electrical stress // J. Annals of Biomedical Research and Education.2006, V.5., issue 1, p L.Gabunia.Effect of Dilatrend and Metoprolol on section parameters of hemocoagulation system // J. Annals ofbiomedical Research and Education. 2006, V. 5. Issue2. p L.Gabunia.Influence of beta-adrenoblokers of the third Generation on Biochemical and Reologic Parameters of Rabbitsblood on the background of the stress, caused by electrostimulation. //J Annals of Biomedical Research andeducation,.2006,.5, Issue 3. p L. Gabunia et al. Morphological investigation of the Nucleus of White Blood Cells at Opiate Dependences and also in Case of Naltreqson Application as an Opiate Antagonist. //J Annals of Biomedical Research and Education. 2006, v.4. Issue 1. p Changes of Blood Coagulation System, Lipid Spectrum and Liver Morphology under the Stress Conditions on the Background of Adrenergic Blockers. // Allergology and Immunology V. 9, # L. Gabunia, T. Vardosanidze et al. Association of Erythrocytes АВО and Rh-Hr Group Antigens with Viral Hepatitis Type C Among Georgian Population Donors. Allergology and Immunology V. 9, # L. Gabunia et al. Comparative Pharmacological and Clinical Analysis of Subutex and

3 Heroin Abstinence Conditions. Bulletin of the Georgian Academy of Sciences. 2006, v. 32. # L. Gabunia et al. Underlying Principles of Arrhythmia Treatment. //Bulletin of the Georgian Academy of Sciences. Seriesof Biology, 2008, V L. Gabunia et al. Influence of Carvedilol on Rheological Properties of Blood under The Conditions of Experimental Electrical Stress //Bulletin of the Georgian Academy of Sciences v. 32. # L.Gabunia et al. Clinical Importance of Modern Beta-adrenergic Blockers Application in the Treatment of Post-infarctionPatients. Experimental and clinical medicine #2 (27). 16. L.Gabunia et al. Peculiarities of Abstinence Condition Developed due to Coaxil Application //Experimental and ClinicalMedicine #6 (39). 17. L.Gabunia et al. Comparative Influence of Dilatrend, Losartan and their Combinations on Lipid Spectrum, Blood Coagulation System and Platelet Quantitative and Qualitative Indices in Experimental Rats // Experimentaland Clinical Medicine N3 (36) L. Gabunia et al. Analysis of Peculiarities of Abstinence Condition Developed due to Tianeptin Application. Georgian Scientific-practical Journal, N Estrogens and Pharmacological Modulation of Estrogenic Receptors // Georgian Medical News N2(167). pp L. Gabunia et al. Pharmacological correction of functional parameters of stressed rat isolated heart working under ischemia Reperfusion condition. Experimental and Clinical Medicine. N6 (39), p. 21. L. Gabunia et al. Comparative Influence of Lizinopril and Lozartan on Rat Heart Isolated According to Langendorf Method under the Conditions of Ischemia and Reperfusion. Experimental and Clinical Medicine N4 (37) p L. Gabunia et al. Effects of Carvedilol, Losartan and Trimetazidin on functional parameters of isolated heartof rats at oxidative stress. Georgian Medical News. N2 (167) pp L. Gabunia, β-adrenoblockers and their role in cardiopharmacotherapy new perspectives of their use. Monograph, L. Gabunia et al. Addictive potential of Tianeptine threatening reality Georgian Medical News, 2009, N L. Gabunia et al. Mechanisms of lead-induced poisoning // Georgian medical news. N7-8 ( ) L. Gabunia et al. Comparative study of influence of Aliskiren, Enalapril, Losartan and Enalapril/Losartan combination onblood coagulation, morphological changes in myocardium and lipid content in rats with Doca-salthypertension. Proceedings of the Georgian National Academy of Sciences. Biomedical series N5-6.T. 38. P L. Gabunia et al. Modern aspects of research ethics //Experimental and Clinical Medicine//2013. N4.p Kh. Pochkhua, Sh. Khetsuriani, K.Khetsuriani, L.Gabunia. Byological characteristics of staphylococcus aureus multiresistant strains. Experimental and Clinical Medicine (Georgian Ref. Journal, wwwtech.caucasus.net). N2, P L. Gabunia et al. Aliskiren - A new era in the treatment of hypertension - abstract in abstract book of conference - Natural and synthetic biologically active substances. P Tbilisi

4 30. Kh. Pochkhua, Sh. Khetsuriani, K.Khetsuriani, L.Gabunia. Enzymes were detected in Staphylococcus aureus strains. Experimental and Clinical Medicine (Georgian Ref. Journal, wwwtech.caucasus.net). N1,2014.p , Shorena Khecuriani, Eka Ekaladze. Methodological recommendations - basics of Scientific research-skilss Tbilisi.Georgia. 32. Kaladze T., Varazi E., Gabunia L., Khetsuriani Sh., Comperative study of influence of Aliskiren, Enalpil, Losartan and Enalapril/Losartan combination on blood coagulation, morphological changes in myocardium and lipid cotent in rats with doca-salt hypertension (abstract). Ukrainian Medical Journal of Young Scientists Chyst. 2015, T.17. p Janjgava M., Khetsuriani Sh., Gabunia L. Enzyme activity and carbohydrate fermentation in staphylococcus aureus strains. (abstract). Ukrainian Medical Journal of Young Scientists Chyst. 2015, T.17. p Gongadze N., Gabunia L., Mirziashvili M.,, Gvishiani M., Archvadze A. Soluble epoxide hydrolase as a new target for therapeutic intervention. Tbilis State Medical University Collection of Scientific works. XLIX/ ნ.გონგაძე, ლ.გაბუნია, მ. გოგოლაური, მ.მირზიაშვილი, ა. არჩვაძე ანტიჰიპერტენზული საშუალებების კომბინირებული გამოყენების მექანიზმები და ეფექტები. ექსპერიმენტული და კლინიკური მედიცინა N1, 2015 წ. გვ , Ketevan Gambashidze, David Vadachkoria, Shalva Petriashvili Effect of Carvedilol and Nebivolol on Biochemical and Rheological Parameters of Blood in Rabbits Stressed With Electrical Current - Georgian Biomedical Journal.2017 April, volume 1, Issue 4, pp ლ.გაბუნია, შ.ხეცურიანი. მონოგრაფია ბიოსამედიცინო კვლევების პრაქტიკული საკითხები. მეცნიერებისა და ინოვაციების თბილისის ფესტივალი თბილისი, თსსუ. 37. R. Beriashvili, L.Gabunia, N.Gamkrelidze, Sh. Khetsuriani. Research Skills Curriculum for Undergraduate Students at Tbilisi State Medical University.11-th Orpheus Conference. 10 th march 12 th Publicatected at abstract book. 38. L. Gabunia, D. Vadachkoria, N. Asatiani, M. Murdalashvili, T. Gamkrelidze, K.G. Gambashidze, N.G. Pkhaladze, M.Z. Pkhaladze Characteristics of Muggituse (dextromethorphan) Abuse. Experimental and Clinical Medicine (Georgian Ref. Journal, wwwtech.caucasus.net) L.gabunia - abstract Actuality of polypragmasy and rational pharmacotherapy in Georgia (World Congress on Pharmacology and Chemistry of Natural compounds, Tbilisi, Georgia. October ). Abstract book. 40. მეცნიერებისა და ინოვაციების საერთაშორისო ფესტივალი 2017 კონფერენციების ჯანსაღი ცხოვრების წესი მეცნიერული მტკიცებულებები და საკამათო საკითხები და ინოვაციები მედიცინაში მოხსენებების მასალათა კრებული. სექტემბერი, 2017 წელი. თბილისის სახელმწიფო სამედიცინო უნივერსიტეტი. 41. ნ. გონგაძე, ლ.გაბუნია, მ. გვიშანი, თ. მახარაძე - საკვები პროდუქტების და მასში შემავალი აქტიური ინგრედიენტების ზემოქმედება წამალთა მეტაბოლიზმზე და ეფექტურობაზე Experimental and Clinical Medicine (Georgian Ref. Journal, wwwtech.caucasus.net) ( in print)

5 42. L.Gabunia, M. Gvishani, M. Gogiberidze - The Influence of Food products on drug Efficacy. BIMCO JOURNAL abstract book of the congress BIMCO,2018.p Zero of neuropeptide -gamma in the development of cardiovascular diseases. Biomedical Journal of the Georgian Academy of Science Biological Series (in print) 44. Role of endothelin 1 in arterial hypertension. Tbilisi State Medical University Collection of Scientific works (in print). 45. Diurnal variability of endothelial function in cardiovascular diseases. Georgian Medical News (in print) 46. Gabunia L., Khetsuriani Sh., Gamkrelidze N., DelibaShvili D., Gumbaridze L. - Issues of Research Ethics and Project Quality Assessment - Scientific Research Skills Center, Tbilisi State Medical University - Georgian Medical News (in print). ტრენინგები და კონფერენციები 1.The IV international conference Biological Fundamentals of Individual Receptivity to Psychotropic Substances. Moscow. March 13-16, Peculiarities of Opiate Agonist-antagonistBuprenorphin Abstinence Syndrome.(abstract); 2. XI INTERNATIONAL EUROASIAN CONGRESS OF SURGERY AND CASTROENTEROLOGY. BAKU,12-15 June, 2008 COMPERATIVE INFLUENCE OF DOXSAZOZINE AND NEBIVOLOL ON LIPIDSPECTRUM, HEMOKOAGULATION SYSTEM AND MORPHOLOGY OF LIVER AT ELECTRICALSTRESS (abstract); 3. The III Congress of Georgian Cardiologists. October 8, Global Day of Heart. Assessment of Antioxidant Activity According to Changes of Isolated Heart Functional Parameters under the Conditions of Oxidative Stress. (abstract); 4. International significance conference was conducted In Vivo EPR in Medicine March Hanover, Newhemsher,the USA. Neuroprotective effect of Plaferon-LB at cerebral infrction in animal models (abstract). 5. The first International Conference Healthy Woman, June, Tbilisi, Georgia Role of Estrogensin Treatment and Prevention of Postmenopausal Osteoporosis (abstract). 4. III INTERNATIONAL CONGRESS MODERN IN ALLERGOLOGY, IMMUNOLOGY AND MEDICAL BIOTECHNOLOGY. II INTERNATIONAL CONGRESS HEALTH AND DRUGS Comparative Influence of Karvedilol and Aspirin on Platelet Quantitative qualitative Indices and Blood Ion Exchange in The Conditions of Experimental Electrical Stress (poster session) (Tbilisi, Georgia). 5. IV INTERNATIONAL CONGRESS MODERN IN ALLERGOLOGY, IMMUNOLOGY AND MEDICAL BIOTECHNOLOGY. III INTERNATIONAL CONGRESS HEALTH AND DRUGS - Changes in the hemocoagulation system, lipid spectrum and the morphological picture of the liver in the condition of the electrical stress and their pharmacological correction (poster Session) (Tbilisi, Georgia). 6. The III Congress of Georgian Cardiologists. October 8, Global Day of Heart. Report on the subject Assessment of Antioxidant Activity According to Changes of Isolated Heart Functional Parameters under the Conditions of Oxidative Stress (oral presentation). 7. XXIV International School-Conference for Medics Modern Clinical Medicine Achievements and

6 High Technologies (Medical and biological aspects of life quality improvement). Influence of Carvedilol on Isolated Heart Functional Parameters under the Conditions of Oxidative Stress (oral presentation) (Tbilisi, Georgia). 8. XXII International School-Conference for Medics Modern Clinical Medicine Achievements and High Technologies - Comparative Influence of Lysinopril andlozartan on Performance of Heart Isolated According to Langendorf Method under the Conditions ofischemia and Reperfusion (oral presentation) (Kobuleti, Georgia). 9. XXIII International School-Conference for Medics - BloodRheological Properties Pharmacological Correction through Antithrombotic Agents at Cardiovascular Diseases (oral presentation) (Bakuriani, Georgia). 11. Conference - Role of Zinc for Human Organism and Its Application at Different Diseases organized by Georgian Nutriciology Association. (State accreditation N ).2008.Tbilisi,Georgia. 12. International significance conference was conducted In Vivo EPR in Medicine - Neuroprotective effect of Plaferon-LB at cerebral infarction on animal models ( oral presentation) Hanover, Newhemsher, the USA. Under the leadership of Dartmouth Medical School Radiology,Physiology and Chemistry Departments. Professor, EPR laboratory director Mr. Harold M. Swartz. 13. The first International Conference Healthy Woman, Member oforganizing committee. Mediator of poster section Age and related Problems. Oral presentation Role of Estrogens in Treatment and Prevention of Postmenopausal Osteoporosis Tbilisi, Georgia. 14.Conference of the Tempus Project Programme Modernizing Undergraduate Medical Education in Eu Eastern Neighboring Area (MUMEENA). Oral presentation - Study of Scientific Resarch Skills at Tbilisi Stat Medical University november. Ukraine. Kiev th international conference - Health and Ecology held in Tskaltubo,Georgia on October, 2012 (oral presentation). 16. One of the organizers TEMPUS MUMEENA conference. Organizer of students second international conference - The way to research. Head of organizing committee Tbilisi, Georgia. TSMU. 17. Participant of Workshopon Strategies for Success in Proposal Writing, CRDF-Global, Tbilisi Participant of WorkshoponAutorship of Peer-Reviewed Publications and International ConferenceParticipation CRDF-Global. Tbilisi. 2012; 19. Participant of Symposium - Main Strategies of Medical Education in 21st Century Tbilisi, Participant of WorkshoponStrategiesforSuccess in ProposalWriting and authorship of Research articles, CRDF-Global, Tbilisi. 2012; 21. Second Scientific Conference natural and synthetic biologically active substances Aliskiren - A new era in the treatment of hypertension (oral presentation). Tbilisi Participant of training - English for Scientific Purposes. CRDF-Global,Bakuriani Participant of training of CRDF GLOBAL Workshop on Strategies for Success in Proposal Writing and Authorship of Resseach Articles Tbilisi, Georgia. 24. Organizer and trener of training for students and young scientists of TSMU - "Basics of Scientific Research-Skills"2014. Tbilisi, Georgia 25.International Conference - Microbial ecology of Enuironmental pathogens - Enzime activity and carbohydrate fermentation in multiresistant staphilococcus aureus strains (poster presentation). 2014, Tbilisi, Georgia. 26. Participant ofi National Conference "Bioregulative Medicine - priorities, safety of and perspectives Tbilisi, Georgia.

7 27. Participant of Conference - OMI SATELLITE SYMPOSIUM ON MEDICAL EDUCATION Tbilisi, Georgia. 28.Participant of training of CRDF GLOBAL Workshop on Strategies for Success in Proposal Writing and Authorship of Resseach Articles Tbilisi, Georgia. 29. Participant in the Medical Laboratory Qualification Program examinations in Tbilisi, Georgia during February 2015 (Defense Threat Reduction Agency Cooperative Biological Engagement Program). 30. Participant of Multiprofile Medical Conference International standards of clinical practice which was organized by Georgian Physicians Postgraduate Association - Antihypertensive drugs combined using s mechanism of action and effects, Ethics in the Phases of clinical research (oral presentations) Bakuriani, Georgia. 31.Participant of the workshop by the German Academic Exchange Service (DAAD) Research Proposal Writing. March 13, 2015 in Tbilisi/Georgia. 32. Participant of Conference actual issues of of modern medicine (Seed of Georgia) Tbilisi. Georgia. 33. Participant of Conference - Second International Medical and Pharmaceutical Congress of Students and Young Scientists - Actual matters of modern medicine and pharmacy (Bukovinian International Medical Congress - BIMCO, Ukrane, 2015, 8-10 april) Development Scientific Research-Skills in TSMU (oral presentation). 34. Organizer of Scientific Conference - "Healthy lifestyle, scientific evidence and disputed matters" Tbilisi, Georgia, TSMU. 35. Organizer of Students Scientific Conference - Matters of Pharmacological interaction between drugs at their combined using Tbilisi, Georgia, TSMU. 36. Participant of European Union of Tempus Programme International Conference - Improving Academic Standards in Education Tbilisi, Georgia. 37. Participant and organizer Scientific Conference for young scientists - "The ethical aspects of scientific research", whichconducted in the frame of Science and Innovations International Week ", organized by the Ministry of Education and Science of Georgia Tbilisi, Georgia. 38. Participant, organizer and trener of training Presentation and publication of scientific research" Tbilisi, Georgia, TSMU. 39. participated in an Omi Satellite Symposium in Effective Use of Medical Simulations under the auspices of the children s hospital of Philadelphia (the American Austrian foundation). October 17-18, Tbilisi, Georgia. 39. luiza Gabunia participated in the Multiprofile Medical Conference International standards of clinical practice which was organized by Georgian Physicians Postgraduate Association. Title of report Ethics in the Phases of clinical research february, 2015 y, Bakuriani. 40. luiza Gabunia participated in Bukovinian International Medical Congress IV International Medical and Pharmaceutical Congress of Students and Young Scientists - Ïnnovations and Prospects of Modern Medicine (5-7 april, Chernivtsi, Ukraine). 41. R. Beriashvili, L.Gabunia, N.Gamkrelidze, Sh. Khetsuriani. Poster section. Research Skills Curriculum for Undergraduate Students at Tbilisi State Medical University.11-th Orpheus Conference. 10 th march 12 th has attended the confeense entitled MSCA Tbilisi, organaised by TEAMWORK ON BEHALF OF THE European Comission on 17 January, in Tbilisi. 42. The American Society for Microbiology Certificate of Participation awarded to to certify participation in the ASM Workshop on Scientific Writing and Publishing. Tbilisi, Georgia, 23 February, was awarded a grant for networking to facilitate the participation of EaP countries in brokerage event - The ICT Proposers' Day 2017, Budapest, Hungary on 9-10 November was one of the organizers of the International Festival of Science and Innovation in Georgia at TSMU (Tbilisi, 24/10 8/ ).

8 45. has participated in World Congress on Pharmacology and Chemistry of Natura Compounds and was awarded Certificate for her Phenomenal and worthy poster presentation on actuality of polipragmasy and rational pharmacotherapy in Georgia. (October 09-11, 2017, Tbilisi, Georgia). 46. ლუიზა გაბუნია. მოხსენება პოლიპრაგმაზიისა და რაციონალური ფარმაკოთერაპიის აქტუალური საკითხები. კონფერენცია ინოვაციები მედიცინაში. მეცნიერებისა და ინოვაციების საერთაშორისო ფესტივალი წ. 28 სექტემბერი. თბილისი. თბილისის სახელმწიფო სამედიცინო უნივერსიტეტი. 47. ლუიზა გაბუნია იყო ორგანიზატორი თსსუ ის სამედიცინო ფარმაკოლოგიის დეპარტამენტის კონფერენციის ცენტრალური ნერვული სისტემის დაავადებები და მათი მკურნალობის ახალი მიდგომები.თბილისი, თსსუ, 2017 წ. მაისი 48. ლუიზა გაბუნიას მოხსენება საკვები პროდუქტების გავლენა წამალთა მეტაბოლიზმზე და ეფექტურობაზე წ. 16 თებერვალი. ბაკურიანი. XV პოლიპროფილური სამედიცინო კონფერენცია. 49. Successfully attended at conference innovations in Brain Tumor Surgery and Radiation Oncology Confeence, on February 2 nd, Organized by American Hospital/KOC University Hospital. 50. read lecture as invited lecturer on the opening Ceremonial V International Medical and Parmaceutical Congress of Students and young Scientists - BIMCO Actual Issues of Rational Pharmacotherapy and Polypragmasy. Ukraine, 4 april ლუიზა გაბუნია მონაწილეობას იღებდა ვორკშოპში: Development of Institutional Animal Care Committee System in Georgia: Facts and Challenges. აპრილი, 26-28, 2018, ბორჯომი, საქართველო. 53. ლუიზა გაბუნია მონაწილეობას იღებდა საერთაშორისო კონფერენციაში ადამიანის გენომი და ჯანმრთლობა. თბილისი, 2018, მაისი (10 - CPE კატეგორია, ოქმი N1, 28/03/2018). Mother tongue(s) Georgian Other language(s) UNDERSTANDING SPEAKING WRITING Listening Reading Spoken interaction Spoken production English C1 C1 C1 C1 C1 Russian C2 C2 C2 C2 1 C1 Levels: A1 and A2: Basic user - B1 and B2: Independent user - C1 and C2: Proficient user Common European Framework of Reference for Languages C1

9 Communication skills - verysociable - very active,creative - ability of working underpressure Organisational/ managerial skills - good organisationalskills - good team-leadingskills Job-related skills - High personal commitment andreliability - Independent - Dependability - Well Organization anddeliberation Digitalcompetence SELF-ASSESSMENT Information processing Communication Content creation Safety Problem solving Independent user Independent user Independent user Independent user Independent user Digital competences - Self-assessment grid

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